Chronic idiopathic polyneuropathy of a primary demyelinating type developed in a man who had had recurrent herpes simplex 2 for 10 years. The pattern of tissue damage is suggestive of an immunologically mediated mechanism. On the sound medical‑scientific evidence available, the Repatriation Medical Authority is of the view that it is more probable than not that trigeminal neuropathy and death from trigeminal neuropathy can be related to relevant service rendered by veterans or members of the Forces under the VEA, or members under the MRCA. This syndrome was associated with autoantibodies to ganglionic nicotinic acetylcholine receptors (G-AChR ) in 1998  . Ali describes his guidelines for gentle daily bowel detox and colon cleanse. More recent evidence has demonstrated that proinflammatory cytokines, including IL-1β, induce a long-term alteration of synaptic transmission in the central nervous system, and that spinal expression and release of these cytokines plays a critical role in the development and maintenance of neuropathic pain of peripheral origin [3–6]. Furthermore, whilst neuropathic pain is a devastating response to nerve injury, it is not the usual consequence, as most patients do not develop neuropathic pain following nerve injuries.
In addition to the presence of intraocular inflammation, vasculitis and retinal necrosis, the authors identified several other characteristics that supported the diagnosis of ARN. The onset of the analgesic effects was observed between 1–5 weeks post-injection and sustained without decrement for at least 7 weeks. Prescribing of therapy with little evidence of efficacy in neuropathic pain is still common in the UK and consequently treatment is often not in line with current guidance. When selecting a particular medication, the National Institute for Health and Care Excellence (NICE) recommends considering comorbidities, safety considerations, contra-indications, patient preference, lifestyle factors, any history of mental health problems (eg, anxiety, depression) and existing medication history. Neuropathy can take several forms. One form (peripheral neuropathy) damages nerves of the peripheral nervous system, and can be caused by disease or other illness. Neurologic examination revealed symmetrical tetraparesis (4/5 on the Medical Research Council scale), upper thoracic sensory level, impaired vibration sense, increased deep tendon reflexes, and extensor plantar responses. 2001; Goss et al.
To this end, we used a recently developed computational algorithm (http://jura.wi.mit.edu/bioc/siRNA) to narrow down a working list of siRNA sequences for Nav1.3.24 This bioinformatic analysis of Nav1.3 produced a short list of ten Nav1.3-specific and potentially effective molecules, as well as a scrambled control sequence, that were advanced for experimental validation. However, these preparations do not heal the inflammations produced by the Herpes viruses. Symptoms typically start bilaterally in the toes and feet, and progress to affect the lower legs. Merck mentions Acyclovir as having shown promise in the treatment of Herpes. For other Herpes lesions, Merck suggests “drying lotions” such as Camphor Spirit or 70% alcohol, and for Herpes Zoster, Merck states “there is no known specific therapy.” Hormones represent another class of anti-inflammatory compounds. However, no known hormones have produced a satisfactory response in the treatment of Herpes inflammation or lesions.  In many topical ointments, zinc oxide is frequently used.
However, it is used as a secondary component, and not the active agent that produces the healing effect. In the prior art, zinc oxide is used as an excipient, filler, surfactant, or sun-blocking agent. To date, the prior art has not produced a topical treatment in which zinc oxide, having sufficiently high concentration levels, has not been used as the active ingredient the treatment of these disorders. Rather, it is typically used as a secondary component that is there to facilitate effectiveness of the primary active ingredients by acting as an excipient, a sun block, or bulk filler. Nerve conduction study was performed on the four limbs showing normal motor and sensory potentials in term of amplitude and velocities, however, F and H waves were absent in both tibial and peroneal nerves. Healing Seminar 10 – Acid-Alkali Balance Professor Majid Ali explains the importance of acid-alkali balance in health preservation and the reversal of chronic disease. The zinc oxide is used in conjunction with excipients, such as baby oil or petroleum jelly to facilitate spreading and application of the zinc oxide onto the surface of the patient’s skin.
However, this model has not been widely adopted, presumably because of the expenses of lasers. Figure 2. Compared to morphine, endomorphins show more potency in neuropathic pain conditions and may produce less undesired side effects .  The invention is a topical ointment for application to skin surface areas suffering from neuropathy, shingles, or other viral infections such as various Herpes types. In the preferred embodiment, zinc oxide is used as the active ingredient in the treatment of these ailments. The topical ointment provided by the invention uses high concentration doses of zinc oxide on the order of approximately twenty five, or more, percent (25%) or more. The remaining component of the ointment is an excipient to allow the zinc oxide to be spread easily on the patient’s skin, and to help secure the zinc oxide to the patient’s skin.
NP2 exemplifies a generalizable HSV vector mediated gene transfer platform that can be employed to deliver genes to DRG neurons by intradermal inoculation, an approach that has been termed the nerve targeting drug delivery system (NTDDS). To confirm transduction efficiency following DRG injection in adult rats, we first used a control AAV2/5 virus-expressing GFP. Most important, it acts as a therapeutic agent for the treatment of shingles, herpes, etc. The research about massage therapy and pain in general is extremely promising. Thirdly, it provides a topical anesthetic effect to soothe an infected area. The ointment does not heal shingles or herpes. What it does is provide an effective method of reducing pain and discomfort associated with these conditions while the body heals itself.
It is been found that the zinc oxide is more effective when applied in high concentration levels of approximately 25% or more. Of course, a portion of the ointment requires the use of an excipient to allow the zinc oxide to be easily applied to skin surfaces.  The ointment can be used for a variety of conditions. For example, individuals with restless leg syndrome often have difficulty sleeping due to a pins-and-needles sensation in their legs. The ointment is effective in reducing this sensation so that individuals can sleep better. In our case, the AChR antibodies were found absent and G-AChR serum antibodies test was not available, however, negative results would not exclude the diagnosis of AAN. The answer:science is dumbed down and doctors know only symptom suppression with drugs.
This process should be repeated as needed. Omana‐Zapata and colleagues demonstrated in axotomized rats that i.v. In ARN-associated optic neuritis, optic disc hyperfluorescence will often occur (Fig. Lentiviruses encoding SHG or Endomorphins were used to transduce a neuroblastoma cell line (SH-SY5Y). The purpose of the sock would be to keep the ointment on and in contact with the skin as long as possible. Further, since the ointment is inexpensive, it allows the patient to shower when convenient and then reapply a fresh layer of ointment.  An advantage of the invention is that it can be inexpensively provided to the public as a nonprescription treatment that can be applied directly by the patient.
In an era of high health care costs, the ability to provide an inexpensive method of treatment carries significant advantages for the ordinary consumer.  Those skilled in the art will recognize that various changes can be made any ingredients used in the zinc oxide ointment. We explored the potential crossover effect of shRNA-B and shRNA-C on other sodium channel isoforms. Likewise, the percentage of zinc oxide can be varied to any suitable amount so long as its ability to be conveniently spread on skin surface, and to remain adhered to skin surface, is not impacted. Further, the viscosity of a topical ointment can be varied. For example, it can be a thick paste, or an easily spreadable cream. The only requirement is that it thoroughly covers the effected area and does not inadvertently separate from the skin surface.
 Another advantage of the invention is that it does not require any drugs or other ingredients. The zinc oxide only requires a suitable excipient to allow it to be applied. The excipient can be baby oil, petroleum jelly, or any other suitable excipient cream or a combination of any of the foregoing.  In an alternative embodiment, the ointment can be made from an excipient, such as baby oil or petroleum jelly, zinc oxide as the active ingredient for pain relief, and capsaicin and/or aspercreme for pain.  While specific embodiments have been discussed to illustrate the invention, it will be understood by those skilled in the art that variations in the embodiments can be made without departing from the spirit of the invention. For example, the proportion of ingredients can vary, the type of excipients can vary, bulking agents can be ended, etc. Oxford: Oxford University Press :267–288.