Ocular manifestations of herpes simplex virus (HSV) infections occur as either primary or recurrent episodes and are typically due to HSV type 1. HSV ocular infection is the most frequent cause of corneal blindness in the US. In the article text, the words “Nanjing First People’s Hospital” under the section “Methods” and sub-section “Subjects” are incorrect instead it should read as “Nanjing First Hospital”. Similarly, the prophylactic treatment of herbal extracts limited the development of recurrent skin lesions induced by stripping with cellophane tape physically. It states that the diseases is caused by herpes simplex virus (HSV) one or two and further adds that it is the cause of corneal blindness in the industrialized world. Supported in part by grants (CA 06973 and CA 15396–08) from the National Cancer Institute, National Institutes of Health, Department of Health and Human Resources, Bethesda, Maryland, and from grants provided by the Burroughs Wellcome Company and the Harley W. Editorial.
Discusses the study of the effectiveness of acyclovir as a prevention for recurrent occular herpes simplex virus (HSV) disease which was conducted by the Herpetic Eye Disease Study Group. Stromal keratitis poses a greater threat of vision loss than epithelial keratitis. Whether pre-emptive therapy or prophylaxis with ganciclovir is the optimal approach against CMV remains controversial, and the relative merits and limitations of each approach may guide the choice. Evaluation of patients under blind conditions; Level of plasma acyclovir achieved in the study; Adverse effects seen in a number of patients… Purpose: To report a case of acyclovir-resistant herpetic keratitis in a solid-organ lung transplant recipient that was effectively treated with topical trifluridine. Methods: A case of a 35-year-old female with herpetic epithelial keratitis resistant to acyclovir is described. L.
Herpes simplex viruses (HSV) types 1 and 2 cause infections manifesting as dermatologic, immunologic, and neurologic disorders. Some of the most important manifestations and complications of HSV infection are considered here in a neuroanatomic context. The critical nature of this initial phosphorylation is best illustrated by drug-resistant mutants of HSV that do not express functional TK and exhibit susceptibility to ACV that is reduced by more than 2 orders of magnitude. Reports on the results of a study on the use of acyclovir as treatment for ocular herpes simplex virus (HSV). Effectiveness of the drug; Dosage; Period of treatment; Information on patients studied; Efficacy results; Capability of the drug to reduce the rate of recurrence of ocular and… The article discusses a clinical case about a young woman with unilateral decreased vision. Topics covered include the differential diagnosis in the case, treatment of herpetic eye disease and types of herpetic eye infections.
E. Herpes simplex virus 1 (HSV-1) infection of the cornea leads to a potentially blinding disease, termed herpetic stromal keratitis (HSK) that is characterized by lesions of an immunoinflammatory nature. In spite of the fact that HSK typically presents as a recurrent disease due to reactivation of…