Famciclovir is used in the treatment of herpes zoster; cold sores; herpes simplex, suppression; herpes simplex, mucocutaneous/immunocompromised host; herpes simplex, mucocutaneous/immunocompetent host and belongs to the drug class purine nucleosides. There is no proven risk in humans during pregnancy. Famciclovir 500 mg is not a controlled substance under the Controlled Substance Act (CSA). Despite this stable prevalence, disease due to drug-resistant HSV remains an important problem for many immunocompromised patients, including those with HIV infection. Genital herpes is caused by herpes simplex virus (one of the most common viruses. Thymidine kinase deficiency accounts for approximately 95% of acyclovir-resistant isolates. Moderate Moderately clinically significant.
Avoid combinations; the risk of the interaction outweighs the benefit. Aciclovir is used for the treatment of herpes simplex virus and varicella zoster virus infections, including: 2 12 13. Usually avoid combinations; use it only under special circumstances. Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Disclaimer: Every effort has been made to ensure that the information provided by Multum is accurate, up-to-date and complete, but no guarantee is made to that effect. Multum’s information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill, knowledge, and judgement of healthcare practitioners in patient care.
This material does not endorse drugs, diagnose patients, or recommend therapy. Multum’s information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill, knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2016 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects.
Human cytomegalovirus (HCMV) is another important causal agent in opportunistic infection, which can induce comparable cytopathogenic effects in infected cells (11).