The similarity between the nonhuman primate and human immune systems is a key advantage in the use of nonhuman primates compared with other mammalian models of human disease.13,71,88,94,103,113,125 In addition, the diversity of environmental and infectious disease agents encountered by primates is similar to that of humans, providing nonhuman primates a comparable level of biologic complexity.1 Old World primates, such as macaques and baboons, and New World primates, including squirrel monkeys and marmosets, are commonly used in biomedical research. Because these properties are shared by certain bacteria (rickettsiae, chlamydiae), viruses are now characterized by their simple organization and their unique mode of replication. We screened cartilage and chondrocytes from advanced and non-/early osteoarthritis patients for parvovirus B19, herpes simplex virus-1, Epstein Barr virus, cytomegalovirus, human herpes virus-6, hepatitis C virus, and human endogenous retroviruses transcripts. Many researchers will view the publications as the end to a contentious debate. This suggests that these tumours are purely virally driven, at least in the early stage. The International Agency for Research on Cancer (IARC) reports that biological carcinogens cause 18-20% of cancers . All living things have hundreds or thousands of genes imported by viruses.
Full text Full text is available as a scanned copy of the original print version. Because host cells do not have the ability to replicate “viral RNA” but are able to transcribe messenger RNA, RNA viruses must contain enzymes to produce genetic material for new virions. Links to PubMed are also available for Selected References.