Cicatricial entropion caused by asymptomatic allergic conjunctivitis

Cicatricial entropion caused by asymptomatic allergic conjunctivitis

Cicatricial entropion caused by asymptomatic allergic conjunctivitis
Presenting complaints include pain, irritation, decreased vision or foreign-body sensation. We present two consecutive patients with cicatricial entropion as the heralding sign of allergic blepharoconjunctivitis. External examination was unremarkable, and there was no evidence of afferent pupillary defect. To help, the October issue of Review of Cornea & Contact Lenses is devoted to broadening your knowledge of the management of different corneal infections. Slit lamp examination revealed marked conjunctival scarring of all four eyelids in each patient. Ocular surface specimens from healthy individuals (n=10) and from patients with suspected viral surface disease (n=19) were studied. RESULTS There was no TN2 immunopositivity in normal corneas except at the corneoscleral interface.

“Pain without stain” was the topic that Stephen Pflugfelder, MD, Baylor College of Medicine, Houston, focused on at the 2014 American Academy of Ophthalmology (AAO) meeting last October. Aggregations ofinflammatory cells were found at 1 hour in the limbal epithelium, 2 hours in the perilimbal conjunctival epithelium, and 3 hours in the peripheral corneal epithelium.In eyes receiving exposure for 4 hours, the infiltration of the inflammatory cells can still be detected at 8 hours after closing eyes.Immunohistochemical study demonstrated the cells to be macrophages, neutrophils, CD4-T cells and CD-8 T cells.SEM demonstrated time-depending increase of intercellular border and sloughing of superficial epithelial cells in corneal surface.

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