Clinical and morphological characteristics of herpes zoster in south India

Clinical and morphological characteristics of herpes zoster in south India

Clinical and morphological characteristics of herpes zoster in south India
Of the more than 100 known herpesviruses, 8 routinely infect only humans: herpes simplex virus types 1 and 2, varicella-zoster virus, cytomegalovirus, Epstein-Barr virus, human herpesvirus 6 (variants A and B), human herpesvirus 7, and Kaposi’s sarcoma virus or human herpesvirus 8. The sample consisted of 20 ulcerative lesions from 15 children treated with chemotherapy in the Pediatric Service of the Regional Hospital of Concepción, Chile. The survival characteristics of HSV on manikin skin also were explored, demonstrating greater than four hours of viability. A nested case-control analysis was used to assess factors associated with an initial episode of herpes zoster. Rape survivors were more likely than women who denied recent rape to smoke crack cocaine (86.8 versus 56.7%; odds ratio [OR] 5.0, 95% confidence interval [CI] 3.2-7.8), to be homeless (17.2 versus 6.1%; OR 3.2, CI 2.0-5.2), to report a recent sexually transmitted disease (38.7 versus 18.7%; OR 2.7, CI 1.9-3.9), and to be infected with syphilis (42.4 versus 28.4%; OR 1.9, CI 1.3-2.6) and HSV-2 (71.9 versus 57.5%; OR 1.9, CI 1.3-2.8). Thoracic dermatome was the most common dermatome involved in 64 (59.8%) cases followed by cervical in 17 (15.8%) cases. However, in binary regression, it was only marital status and family history of herpes labialis that emerged as the determinants of this lifetime prevalence.

Forty six cases were screened for HIV, out of them; six cases (4 males, 2 females) were seropositive for HIV. Classical herpes zoster was a feature in four cases; however, one case each also had necrotic and hemorrhagic form of herpes zoster. The mean duration to cure was 40.9 days.

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