It has long been speculated that viruses are the root cause of multiple sclerosis (MS). In Part 2, we looked at omega-6 fats in industrial pork meat and toxins in processed pork products as possible causes (The Trouble with Pork, Part 2, Feb 15, 2012). And has proven about as difficult to crack. The study was published in an advance online edition of the journal Annals of Neurology and will appear in a later print edition. According to most researchers, the interaction of several factors including the environment, genetics, and viruses can lead to MS. This is why it is so important to recognize your triggers in order to minimize the symptoms. However, researchers have recently been able to identify which immune cells are mounting the attack; how they are activated to attack; and some of the sites, or receptors, on the attacking cells that appear to be attracted to the myelin to begin the destructive process.
The absence of IL-17 production in infected mice suggests that the disease might be triggered by different T cell subsets than typical EAE. Genain. It is possible that infections could lead to Multiple Sclerosis. (Parallels are seen in the increasing severity of pneumonias caused by Chlamydia pneumoniae in those who suffer repeated infections after seroconversion: the severity is caused by the increasing strength of the host response.) In the progressive forms the host response is continuously firing, often against an extracerebral bacterial infection; a patient with early SPMS will often mention chronic sinusitis, chronic middle ear disease or new-onset asthma which began some time before the MS began to slide into the progressive phase. This is the first published large-scale study suggesting an association of a human herpes virus in the disease process of MS. Moreover the researchers noted MS is extremely rare in people who have never had an EBV infection. The type of neurologic deficit may indicate, to some extent, the location of the damage to the nerves.
It is virtually unheard of in places like Malaysia or other areas of the “inter-tropical belt”. Caregivers cannot predict the onset of a relapse, the progression of the disease, or even the patient’s ability to function over the course of a day. Since the existing literature suggests that different mechanisms lead to EBV association with the various autoimmune diseases, we will focus our discussion primarily on MS and refer to SLE and RA only when similarities or differences between these diseases and MS have been clearly defined. One still unproven hypothesis is that a viral infection occurring in genetically susceptible individuals induces the disease. They service medically complex and post-acute patients including, but not limited to the following services: pulmonary care, progressive ventilator weaning, rehabilitation, wound care, dialysis, neuro-sensory stimulation, and overall medical management.