Human herpesvirus (HHV-) 6 has been associated with various neurological diseases, including encephalitis, meningitis, epilepsy, and multiple sclerosis. Sixty percent (93/154) of CFS patients were were positive for HHV-6 EA IgM, 40% (61/154) were positive for IgG, and 23% (35/154) were positive for both. The initial HHV-6 seropositivity was 92% by EIA and 76% by IFA, whereas final testing showed 100% positivity by EIA and 84% by IFA. In HIV-seronegative persons with high risk behaviour for HIV-infection, both IgM and low avidity IgG were frequently found in higher titre, representing either primary or frequent reinfections, or reactivation of latent HHV-6. The statistical analysis was performed with the Cox proportional hazards models. Six hundred and ninety-six serum samples from individuals of different age groups were examined for IgG antibody status. De asemenea virusul a fost detectat in laptele matern.
In these cases, demonstration of the presence of EBV viral capsid antigen (VCA) immunoglobulin G (IgG) and/or IgM antibodies, along with the absence of IgG antibodies to EBV nuclear antigen-1 (EBNA-1), allows the diagnosis of EBV primary infection (9). Clinically, HHV-6 and HHV-7 are the common etiologic agent of exanthem subitum (ES) (roseola) (4, 10, 14, 13). 1986), acquired immunodeficiency virus (AIDS) (Agut et al.