Also referred to as gluten rash or Duhring’s disease, dermatitis herpetiformis is a discomforting skin condition marked by inflammation of the skin and formation of blistering, burning, and itchy skin rashes. Immunofluorescence testing in the diagnosis of autoimmune blistering diseases: overview of 10-year experience. People usually suffer from this particular disease when they get into their twenties. Compounding the problem is the fact that many physicians simply were not educated on diagnosing celiac disease. Contact dermatitis usually does not spread from one person to another, nor does it spread beyond the area exposed to the irritant unless affected skin comes into contact with another part of the body. However, in the case of some irritants, such as poison ivy, contact dermatitis can be passed to another person or to another part of the body. Stasis dermatitis is characterized by scaly, greasy looking skin on the lower legs and around the ankles.
Stasis dermatitis is most apt to affect the inner side of the calf. Nummular dermatitis, which is also called nummular eczematous dermatitis or nummular eczema, generally affects the hands, arms, legs, and buttocks of men and women older than 55 years of age. The leading theory for dermatitis herpetiformis is that a genetic predisposition for gluten sensitivity, coupled with a diet high in gluten, leads to the formation of IgA antibodies against gluten-tissue transglutaminase (t-TG), which is found in the gut. It may also be noted that some persons with dermatitis herpetiformis may suffer from celiac disease without experiencing any kind of intestinal problem symptoms. Most people with DH have some degree of coeliac disease. Dapsone has also been used as symptomatic therapy for DH . Swallow the tablet with a drink of water.
Philadelphia, PA: Elsevier Saunders; 2014:chap 25. Because the protein is stuck to parts of the intestinal tract, the person’s bowels can be irritated, inflamed and damaged by eating gluten. Dermatitis Herpetiformis, also known as DH or Celiac Rash, is a skin condition that produces a cluster of itchy blister-like bumps surrounded by a painful rash. [Medline]. If you take any nutritional supplements, examine them carefully to avoid any iodine containing ingredients. and decided to go gluten free. The dermatologist must obtain a slight skin biopsy from uninvolved skin adjacent to blisters or erosions.
1990 Feb. Middle age. Antibacterials have been known to help with the itching once an outbreak occurs but it is best to note that many medications contain gluten. • For infants suffering from Dermatitis herpetiformis, use primrose oil as well as vitamin B6. Clinical and immunopathological features of 159 patients with dermatitis herpetiformis: an Italian experience. G Ital Dermatol Venereol. 2013 Apr.
148(2):163-9. [Medline]. However, these associations have not been subsequently confirmed by further studies, and they do not seem statistically significant in relation to the HLADQ2 and HLA DQ8 haplotypes. Dermatitis herpetiformis: potential for confusion with linear IgA bullous dermatosis on direct immunofluorescence. It is there that IgA antibodies cross-react with an enzyme in the skin, epidermal transglutaminase (eTG). The sample is examined under the microscope in a laboratory, using a special test to look for antibodies called IgA. This test can reliably diagnose DH.
[Medline]. [Full Text]. Ciacci C, Ciclitira P, Hadjivassiliou M, Kaukinen K, Ludvigsson JF, McGough N, et al. The gluten-free diet and its current application in coeliac disease and dermatitis herpetiformis. Indirect immunofluorescence was not performed, other auto-antibodies were normal. In case of typical findings from DIF (ie, granular IgA deposits at the dermal–epidermal junction or at the papillary tips) and of positive anti-tTG testing, the diagnosis of DH and, accordingly, of CD can be confirmed. 3 (2):121-35.
[Medline]. Thompson T, Dennis M, Higgins LA, Lee AR, Sharrett MK. Gluten free diet survey: are Americans with coeliac disease consuming recommended amounts of fiber, iron, calcium and grain foods. J Hum Nutr Diet. 2005. 18:163-9. Kadunce DP, McMurry MP, Avots-Avotins A, Chandler JP, Meyer LJ, Zone JJ.
The effect of an elemental diet with and without gluten on disease activity in dermatitis herpetiformis. J Invest Dermatol. 1991 Aug. 97(2):175-82. [Medline]. The allergens appear in a wide array of products. Dapsone usually improves the rash quickly.
The gluten-free diet takes longer to help – it may take a year or more to get the full benefit. 2008 Jun 1. 27(11):1140-7. [Medline]. Parents of children who are newly diagnosed with celiac disease will need to speak to their child’s teacher or day care provider about the condition, what foods are safe, and what to do in case of inadvertent exposure to gluten. Malignancies and mortality in patients with coeliac disease and dermatitis herpetiformis: 30-year population-based study. Dig Liver Dis.
2006 Jun. 38(6):374-80. [Medline].