Decision analysis was used in the evaluation of nine strategies for the prevention of neonatal infection with herpes simplex virus (HSV). Effective prevention strategies for HSV-2 infection are needed to achieve the goals of the World Health Organization global strategy for the prevention and control of sexually transmitted infections. A study from Seattle has suggested that the risk of acquisition of HSV during pregnancy was 3.7%. The majority (92%) of physicians performing deliveries asked pregnant women if they had a history of genital herpes. While you cannot absolutely make sure that the partner is being faithful, a reduction in practices such as anonymous sex and one-night stands can significantly reduce the risk associated with genital herpes. Barrier methods include methods such as male condoms, female condoms, and dental dams. This does not completely eliminate the risk of genital herpes transmission, but it does reduce some risk, as well as the risk of contracting other STDs.
As confirmed by Western blot testing, there were 16 HSV-2 seroconversions among women assigned to tenofovir gel as compared with 36 among those assigned to the placebo gel (incidence rate ratio, 0.45; 95% CI, 0.23 to 0.82; P = 0.005). Equivocal results were resolved by western blot. It is important to have some awareness of past sexual history and current sexual health of your partner. Individuals who do have genital herpes are not forever banished from having a sexual relationship, but precautions must be taken, and the individual’s sexual partner must be informed. It is important that both partners recognize the signs of an outbreak and abstain from sexual contact. Even when there is no visible sign of outbreak, it is important to exercise caution and use the above tips to prevent transmission of genital herpes to the unaffected partner. A confirmatory analysis was performed by Western blot testing.
416 maternal cord pairs were tested for HSV-1 antibodies and 330 (79.3%) were positive.