The peptide beta amyloid has long been thought to be involved in Alzheimer’s disease, though there is a great deal of controversy about whether it’s a primary cause of the disease, or merely a symptom. Hingley is involved in two distinct research projects. A protein called beta amyloid, long considered the bad actor in Alzheimer’s, actually plays a positive role in fighting off bacteria and fungus in mice, worms and cells, the researchers showed in a new paper in Science Translational Medicine. Harold Freeman and experts in Alzheimer’s, including Dr. That remarkable preservation across evolutionary time, and the protein’s resemblance to other antimicrobial compounds in the body, led neurobiologist Rob Moir to wonder about the function of amyloid-beta. Since it was a small study, the authors advice conducting a bigger one to investigate the mechanisms by which gum disease may lead to decreased cognition. If we did not know what to do about Alzheimer’s, our best choice might be to accept and reside ourselves to a gradual deterioration of our memory.
“If our brain is functioning properly and working the way it should, it will be able to fight off infection,” he said. Both have clearly been linked to various microbial presences. Therefore, these studies, inaddition to the previous research reported by our laboratory, support an emerging linkage of the infectious processs to the neuropathology characteristic of Alzheimer’s disease. Support for the immune defence idea comes from work by Jacobus Jansen of Maastricht University in the Netherlands. “There’s a tipping point,” he said, but no one yet knows where that is. I suggest taking vinpocetine as part of a nutritional supplement called Super Brain Booster (available from www.wellnessresources.com), which also includes B. Some disease syndromes almost have to be caused by pathogens – for example, any with a fitness impact (prevalence x fitness reduction) > 2% or so, too big to be caused by mutational pressure.
Other work has suggested that infections can cause Alzheimer’s disease, arguing that microbes lead to inflammation, directly causing neuron death and cognitive decline. In the mice, worms and cells the team tested, amyloid helped kill pathogens by surrounding them and caging them in. Such clumps of amyloid have long considered the hallmark of Alzheimer’s Disease.