Full text Full text is available as a scanned copy of the original print version. Later, under conditions of stress or other environmental stimuli, they reactivate to undergo a productive infection and spread to new host organisms. No matter in what form it appears, a herpes virus infection is only treatable. However, a lot of research is being done to find a comprehensive cure. Betsy – The primary strategy that people used in the past really focused on one major protein that that the virus makes, glycoprotein D. A clever virus stays with it. ~ James Lovelock I must say this quote stands eerily true for the herpes virus!
Herpes – there is much more to those blisters than what appears above the surface of the skin. Even when they seem to disappear as an apparent effect of medications and herpes treatment, rest assured that the primary agents of this infection, the Herpes Simplex Virus, is just taking a short nap right there inside your body, resting itself till the next outbreak! Studiile sustin insa ca acesta poate sa fie din ce in ce mai responsabil si de herpesul genital. However, clever as it is, this virus can be said to have a somewhat egotistical personality which drives it to make its presence felt to the host in the form of those occasional outbreaks! Carmen Manciuc, de la Spitalul de Boli Infectioase. Thus, murein prevents redness and are purple (positive). Most of us are aware that not all micro organisms are bad for us.
At least in case of bacteria, yeast and fungi, there are a lot of species with which we have a symbiotic relationship and which are actually directly beneficial for our existence! A virus expressing WT ATF3 showed lower levels of reactivating lytic gene expression, consistent with ATF3 maintaining latent infection. Not all viruses may be significantly harmful to us but as of today, I doubt if any virus species has been shown to possess any benefit for mankind or for any other organism for that matter! With this sentiment running strong for years, a lot of efforts have been invested in herpes cure research which, going by recent reports, promises to permanently evict this infection from the system of the affected. Not only do we protect them from disease, but unlike the previous vaccine candidates, we prevented the virus from establishing what we called latency – the ability of the virus to hide out inside your nerve cells and therefore cause persistent or recurring infections. Speaking of the herpes virus, this tiny speck of genetic bundle is one hell of a smart Aleck! Facts The survival and propagation strategy adopted by this virus is no less than a genius plan chalked out by a guerrilla warrior!
Similar to a guerrilla warrior, the virus lies dormant and inactive within the host, hiding inside the cells of the nervous system when the immune defenses scan the entire body for pathogens. The immune system is unable to detect a pathogen or infection unless it is in an active form. This is true for drugs and medications as well which cannot target a dormant pathogen or an inactive infectious agent. Once the medications leave the blood stream and the immune system has completed scanning the body for pathogens, these viruses come out for a brief time and start bombarding our system which manifests as those occasional outbreaks. Odata cu reaparitia herpesului apar durerile, usturimea, mancarimi unde vor aparea leziunile. Scientists have been able to pinpoint the specific protein in the genome code of the herpes virus which enables it to enter a dormant state inside the host cells. The key to an effective cure for herpes lies in disabling this protein so that the virus cannot hide any more, allowing the anti viral medications to take their course in tackling the infectants once for all.
Even in absence of medication, the immune system itself can take neutralizing action if the virus is in its active form and is exposed to the body’s immune defenses. It is important to consider the two different potential effects of ATF3 discussed in this paper. Its mechanism of action focuses on disabling certain essential proteins called Terminase in the viral genome code that assists the virus to replicate, thereby, inhibiting their further spread inside the host. A vaccine made from the proteins present on the cell surface and various other components of the herpes simplex virus which, if exposed to the immune system, can trigger an immune response is in the process of development. Can you still protect people who have already got HSV-1 against HSV-2 using your candidate? If this project is successful, we will soon have a vaccine that serves the primary purpose of getting the immune system and the virus to come face to face by activating both at the same time! Other researches are also in progress that aim at inactivating the virus permanently inside the host and disrupting the enzymes and genes that the virus needs in order to survive inside the host.
Well, the horizon looks pretty bright and we can expect a herpes cure in the next 10 – 15 years if these researches prove successful on humans. On a parting note, I’d like to share a very interesting yet scary fact about herpes. A person who carries this infection for a very long time develops partial immunity to this virus, experiencing lesser outbreaks in terms of frequency and intensity. Some people even become asymptomatic over long years of carrying the virus. You must be thinking, “So what’s scary about it?”. Well, these people can still pass on the infection to others!