Infection with herpes simplex is one of the most common sexually transmitted infections. Signs/Symptoms How it’s Diagnosed Treatment & Prevention Who should get tested? HSV-II is a sexually transmitted virus that produces genital lesions. Humans are the carriers and the HSV is transmitted by direct contact (kissing, sexual intercourse, oral sex, ect.). The way the virus spreads is usually through physical contact. A few times every year, however, the Herpes 1 virus becomes active and causes an outbreak of sores and fluid-filled blisters around the site of infection. It does this by encoding an “infected” protein called ICP47 (or Infected Cell Protien 47) .
Als men het virus heeft opgelopen blijft deze in het lichaam zitten en komt het onder bepaalde omstandigheden naar voren. HSV-1 predominates in orofacial lesions, and it is typically found in the trigeminal ganglia, whereas HSV-2 is most commonly found in the lumbosacral ganglia . Als men het herpes simplex virus heeft komt dit onder bepaalde omstandigheden naar voren in het lichaam. Meestal komen de infecties in het bovenlichaam naar voren. HSV structural components include an envelope that contains at least eight glycoprotein spikes, a capsid and tegument which surrounds the capsid, and the core that contains the DNA (9). These sores can last from a few days to two weeks, and they may leak fluid and then crust over. For reasons that are only vaguely understood, however, the virus occasionally begins replicating through a process called shedding, at which time it can cause outbreaks of sores and blisters on and around the genitals.