Our patient developed FDE to levofloxacin at multiple new sites in addition to the lesions noticed on the right hand during the first exposure… What is it? The reaction can take hours, days, or even weeks to develop, depending on whether or not there is immunlogic memory of the precipitating antigen. Treatment of Hz includes the use of antiviral agents, analgesics for control of acute zoster pain, good skin care for healing, and prevention of secondary bacterial infection. The disease results from virus particles in a single sensory ganglion switching from their latent lysogenic cycles to their active lytic cycles. In contrast to the herpes simplex virus, the latency of VZV is poorly understood. The incidence of zoster in first decade of life is reported to be nearly 0.74 cases per thousand per year . There was no history suggestive of psoriasis in any family member.
The literature is also reviewed. The commonest segment affected was thoracic (42.4%) followed by cranial (28.2%) and cervical (12.1%). nerves, such as herpes zoster infections (shingles. There is, however, a strong relationship with increasing age. The incidence rate of herpes zoster ranges from 1.2 to 3.4 per 1,000 person-years among younger healthy individuals, increasing to 3.9–11.8 per 1,000 person‐years among those older than 65 years, and incidence rates worldwide are similar. This relationship with age has been demonstrated in many countries, and is attributed to the fact that cellular immunity declines as people grow older. Cellulitis usually appears as a warm, tender area of erythema and is accompanied by a fever and leukocytosis with left shift. The reactivation of the virus causes zoster. Any factors of immunosuppression should be checked, especially HIV, particularly in disseminated and long-lasting cases.