how long will it be for me to have less outbreaks, will it ever go down to say 1 per year.. G207 exhibits an efficient oncolytic activity in tumor cells, yet minimal toxicity in normal tissue when injected into the brains of HSV-susceptible mice or nonhuman primates. Among the participants who received placebo, subclinical shedding occurred on 64 of 928 (6.9%) days compared with 3 of 1057 (0.3%) days among the participants who received acyclovir (P < 0.001). The frequency of induced shedding was 90% of eyes and 100% of rabbits at 90 days after inoculation. i know acyclovir is one, but what is aciclovir? Histopathology revealed normal brain tissues including the sites of inoculation. The mean titer/wash of HSV in the tear film increased gradually from 6.4 x 10 plaque-forming units (PFU) (day 2) to 2.7 x 103 PFU (day 4) and then decreased to 3 x 102 PFU, remaining relatively constant until virus was not detected. The lowest titer was obtained on the first day of shedding (day 4 after the initiation of epinephrine iontophoresis), and the highest titer was obtained on the third day of shedding (day 4 after the initiation of epinephrine iontophoresis). added with condoms what is the risk? The results indicate a highly reliable animal model for the induced appearance of HSV-1 into the tear film. This model can be used for the elucidation of basic mechanisms of the HSV latency-reactivation-recurrence processes.