Limited Variability of Glycoprotein Gene Sequences and Neutralizing Targets in Herpes Simplex Virus Type 2 Isolates and Stability on Passage in Cell Culture

Limited Variability of Glycoprotein Gene Sequences and Neutralizing Targets in Herpes Simplex Virus Type 2 Isolates and Stability on Passage in Cell Culture

Limited Variability of Glycoprotein Gene Sequences and Neutralizing Targets in Herpes Simplex Virus Type 2 Isolates and Stability on Passage in Cell Culture
Herpes simplex virus (HSV) recombinants induce durable immune responses in rhesus macaques and mice and have induced partial protection in rhesus macaques against mucosal challenge with virulent simian immunodeficiency virus (SIV). M. The reactivation phenotype of TG that are latently infected with wild type HSV-1 or with LAT rescued mutant (i.e. The gene product was identified as three polypeptides with apparent molecular masses ranging from 32 to 35 kDa in HSV-2-infected cells, and at least one species was phosphorylated. This suggests that ICP27-responsive elements lie in the transcribed body of the gC gene. In rare instances, a publisher has elected to have a “zero” moving wall, so their current issues are available in JSTOR shortly after publication. Third-order neurons in the thalamus project to sensory cortex that subserves the discriminative aspects of pain perception, and to limbic cortex to subserve the hedonic aspects of the pain experience.

Cells derived from this type of recombination event will be X+/+, neor+ and HSV-tk+ and therefore resistant to G418 but killed by FIAU (a drug that kills cells containing a functional HSV-tk gene, but which is not toxic to cells with only the cellular tk gene). Chirimuuta, and J. Get a printable copy (PDF file) of the complete article (1.5M), or click on a page image below to browse page by page. Complete: Journals that are no longer published or that have been combined with another title.

You may also like