Hi, I’m Dr. Afterwards, some kids have peeling of their hands and feet and they may even develop a nail dystrophy. HFMD is caused by members of the non-polio enterovirus group of viruses,  which includes coxsackieviruses, echoviruses and enteroviruses. Coxsackievirus A16 and enterovirus 71 are the most common cause of HFMD,  but other coxsackieviruses and enteroviruses have also been linked with the illness and its outbreaks. Mouth ulcers may be accompanied by pain, and the affected person may experience a low-grade fever. A case involving a dentist and his family is reported. Romero JR, Modlin JF.
This will enhance the flow of blood to relieve the numbness, pricking and burning sensation. One day before the consultation, he noticed round vesicles on the hands and feet.  Patients with herpes simplex infection and history of drug intake within the preceding 2 weeks (prior to the onset of skin lesions) were excluded from the present study. A total of 62 patients with the clinical diagnosis of HFMD were evaluated (35 males and 27 females, age range: 9 months to 20 years; mean, 60.1 months). Almost all the patients (60, 96.8%) were below 12 years of age. Hand, foot, and mouth disease usually causes mild illness, and most people completely recover in seven to 10 days. Children with HFM disease are most contagious while they have mouth ulcers during their first week of illness.
Thirty-four (54.8%) patients gave a history of abrupt onset of mild to moderate fever. Anorexia (9, 14.5%), malaise (7, 11.3%), dysphagia (6, 9. 7%) and arthralgia (2, 3.2%) were the other symptoms. Cutaneous symptoms, present in 34 (54.8%) patients, included burning sensation (16, 25.8%), mild pruritus (14, 22.6%) and pain (13, 21%). The palms [Figure 1] were found to be the most common (57, 91.9%) site of involvement, followed by buttock [Figure 2] (52, 83.9%), knee [Figure 3] (50, 80.6%), sole (44, 71%) dorsum of feet (21, 33.9%), dorsum of hands (20, 32.2%), elbows (11, 17.7%), heels (11, 17.7%), thighs (5, 8.1%), legs (4, 6.4%), trunk (3, 4.8%), face (2, 3.2%) and genitalia (2, 3.2%). Lack of some types of vitamin and mineral iron in the body can lead to pins and needles in hands and feet, fingers and legs. Antibodies against desmoglein 1 or 3, herpes simplex, and HIV were all negative.
Grayish-white vesicles were the most common type (62, 100%) of cutaneous lesion noted. Vesicular lesions on the palms and soles were characterized by their elliptical shapes. Accompanied perilesional erythema was noted in 57 (91.9%) patients. People with hand, foot, and mouth disease are most contagious during the first week their symptoms appear. One patient had pneumonitis that resolved uneventfully. Submandibular lymphadenopathy was seen in seven (11.3%) patients and leukocytosis was seen in four (6.4%). HFMD was first recognized as a clinical entity in 1957 in Toronto, Canada,  but the name HFMD was first used in 1960 during an outbreak in Birmingham, England.
 The first ever Indian epidemic was recorded in Kerala in 2003.  No racial or gender predilection is recognized for the disease. We have seen a slight male preponderance in our series. Infections, injuries and damages to the tissues are also causes of long term pins and needles. The characteristic features of HFMD in 2011 in Japan were adult cases with severe systemic symptoms, larger skin eruptions, and wider distributions on the face and buttocks besides the hands and feet.