Seroepidemiology and control of genital herpes: the value of type specific antibodies to herpes… – Abstract

Seroepidemiology and control of genital herpes: the value of type specific antibodies to herpes... - Abstract

Seroepidemiology and control of genital herpes: the value of type specific antibodies to herpes... - Abstract
Herpes simplex virus type 2 (HSV-2) is a common sexually transmitted disease, but there is limited data on its epidemiology among urban populations. METHODS: Through convenient sampling, an anonymous questionnaire survey was conducted on female sex workers to collect related information. Herpes simplex virus type 2 (HSV-2) is similarly transmitted and more prevalent and could thus serve as a proxy marker for sexual risk behavior and therefore HIV infection.HSV-2 antibodies were assessed in a sub-study of 70,000 students participating in an education intervention in Western Province, Kenya. Immunocompetent adult patients, enrolled as of January 1, 2011 were analyzed. However, low rates of inappropriate discontinuation of empiric therapy in patients with herpes simplex encephalitis or improved diagnosis and outcome resulting from a negative PCR assay result in patients without herpes simplex encephalitis led to better outcomes with the PCR-based approach. RESULTS: HSV DNA was detected in 23 out of 115 (20%) tear samples. The JIA cohort included 8,503 children with 13,990 person-years (p-y) of follow-up.

All patients who developed varicella received antiviral treatment. Assays of HSV type specific antibodies have been used in seroepidemiological surveys that include information about demography and sexual behaviour to identify risk factors for HSV-2 infection. Reproductive tract infections (RTIs) including sexually transmitted infections (STIs) continue to be major health problem in developing countries leading to considerable morbidity. Other organ systems include the lymph nodes, especially the nodes of the thorax, the skin, the eyes, the liver, the heart, and the nervous and musculoskeletal system. In close partnership with external partners, the WHO/Europe HIV/AIDS, STIs and Viral Hepatitis Programme supports CISID – the centralized information system for infectious diseases. The original study ascertained asthma status by applying predetermined asthma criteria (PAC), which was used for previous studies that showed the association of asthma with increased risks of common and serious microbial infections (e.g., serious pneumococcal diseases, pertussis, Streptococcus pyogenes upper respiratory infection, and recurrent or persistent otitis media).9–12 However, it is unknown whether the original study findings on the association between asthma and the increased risk of HZ are true when a different asthma criteria, e.g., the Asthma Predictive Index (API),13 was applied. Infect.

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