Vaccination and Control of Feline Calicivirus

Vaccination and Control of Feline Calicivirus

At Cats Exclusive we constantly review the latest medical literature to keep abreast of changes that we believe will enhance your cat’s health, including the safest-possible vaccination protocols. In other words, in order to get this kind of infection, a cat must be in the same home as an infected cat or share the same human caretaker, toys or food bowls. If cats are vaccinated at less than 12 weeks of age, a second vaccination should be administered at 12 – 16 weeks of age. Virus neutralization tests were used to determine antibody titers yearly. Therefore, there may not be much benefit of the modified-live vaccine over a killed vaccine. Some cats may receive boosters less frequently than this based on discussions at health checks regarding risk factors. Vaccination for calicivirus produces a “non-sterile” immunity, meaning that it does not eliminate infection or development of a carrier state, but lessens the severity of clinical signs in infected cats and decreases shedding of the virus.

Do not use in kittens younger than 4 weeks of age. bronchiseptica, and all 20 cats were negative for Mycoplasma spp. “Because both vaccines are applied mucosally, we believe they are considered safer alternatives to certain injectable vaccines which are associated with injection-site reactions,” said Ray Cooper, marketing manager for biologicals at Heska. We can not eliminate FCV from multiple cat environments, nor exclude it from veterinary clinics. Adult cats should be vaccinated 1 year after their initial series and every 3 years thereafter. Feline respiratory disease – is often termed ‘cat flu’. Cats and kittens with severe eye infections may also be prescribed a topical antibiotic eye ointment in addition to the oral antibiotics.

Vaccination and Control of Feline Calicivirus
It is important to note that intra-nasal vaccines may induce sneezing, which may be confused with active infection. It should be noted that up to 15% of cats may develop mild “cold” symptoms for 2-3 days after intranasal vaccination. In kittens, herpes infections are notorious for dragging out. No needles are necessary to administer the vaccine. Until recently, licensure of veterinary biologics did not require data on minimum duration of immunity, only that the vaccines were efficacious shortly after vaccination (weeks to a few months). The two strain vaccine does seem to provide better cross protection for traditional calicivirus infections. Feline calicivirus is non-enveloped, and therefore resistant to many common disinfectants.

5% bleach at a dilution of 1:32 has proven to be effective and should be used routinely to clean surfaces and instruments that come into contact with cats, especially those showing clinical signs. Other acceptable cleaners include potassium peroxymonosulfate (Trifectant) and chlorine dioxide. In the vaccinated cats, the Day 1–10 median cumulative clinical score for each cat was 0 (range 0–5). Suspected cases should be kept in strict isolation. So far, no relationship has been discovered between the genetic sequence of a particular strain of calicivirus and the level of virulence. Gowns, gloves, and shoe covers should be utilized. Outbreaks of virulent-systemic calicivirus pose an extreme challenge to shelters.

All exposed cats must be considered at risk of transmitting the disease. There is no defined quarantine period, because the duration of viral shedding and for how long the virus maintains the mutation causing increased virulence is unknown. We use a non-adjuvanted vaccine, which has not been linked to vaccine-site sarcomas. The antibiotics act on these. Due to intermittent shedding, 3 oropharyngeal swabs at 1 week intervals are required. Serologic testing—Blood samples from vaccinates and control cats were collected in evacuated glass tubes 2 months and 3, 4, 5, 6, and 7 years after vaccination, immediately before each viral challenge, and at weekly intervals for 4 weeks after each viral challenge. Often suspected cases of virulent-systemic calicivirus turn out to be an unrelated primary disease (such as panleukopenia) that is confounded by co-infection with traditional FCV.

It is possible these diseases will be more amenable to treatment. Before extreme measures are enacted, care should be taken to rule out this scenario. The likelihood that virulent-systemic calicivirus is involved increases when otherwise healthy adult cats or well-vaccinated cats are affected.

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