A new report from University College London is warning pregnant women to be alert to the dangers of cytomegalovirus (CMV) – a common virus that can lay dormant in a woman’s body for several years but, if she becomes pregnant, may cause serious harm to her unborn baby. In a healthy host, the immune response is usually sufficient to prevent disease, but not strong enough to completely eliminate the virus. As a prelude to biochemical analysis, we have conducted a detailed analysis of the relationships among US12 family members and between these proteins and other proteins, particularly GPCR and other 7TM molecules. Deaths and permanent disabilities associated with congenital CMV infection affect more newborns than Down’s syndrome, fetal alcohol syndrome, or neural-tube defects (Ross, Dollard et al. It rarely leads to serious disease, otherwise it usually causes mild symtoms.CMV is mainly a problem for certain high-risk groups, such as mothers suffering from diseases caused by CMV (cytomegalovirus) causes danger for her unborn baby. Cytomegalovirus, commonly referred to as CMV, is a member of the herpesvirus family. In the 16th Century, Shakespeare also described the effects of herpesvirus infection in humans in “Romeo & Juliet.” In Mercutio’s speech about Queen Mab, he wrote, “O’er ladies lips, who straight on kisses dream, which oft of the angry Mab with blisters plagues…” Shakespeare was talking about the characteristic lesions caused by Herpes Simplex Virus (HSV), more commonly known as cold sores or fever blisters (shown in the picture below).
Once the CMV virus is in a person’s body, it stays there for life. The few published reports on these conditions focus either on immunocompromised transplant recipients who are receiving high-dose immunosuppressive agents or on HIV-infected patients [5–11].