Viruses Can Cause MS

Viruses Can Cause MS

ST. They found the traces of EBV infection in immune cells (B cells and plasma cells) that had infiltrated the brain in 21 out of 22 brains from people with MS, but not in brains from people who had other neurological diseases that, like MS, involve inflammation. In recent years, however, researchers have been able to identify which immune cells are mounting the attack, some of the factors that cause them to attack, and some of the sites, or receptors, on the attacking cells that appear to be attracted to the myelin to begin the destructive process. Hundred of thousands of individuals not infected with EBV were followed up for several years through repeated blood samples collections. However, this may not necessarily be the case. When the tissue damage is severe, cell death can lead to permanent nervous system disability. To date, researchers have not been able to identify a single virus as the trigger for MS.

Viruses Can Cause MS
Sometimes, however, MS goes into permanent remission. Studies find that if you have a family member with Multiple Sclerosis then you are 5 percent more likely to get the disease. Other viruses are known to target specific cells in the central nervous system. Indeed, investigators have been surprised at how frequently pathogens pass back and forth. Not long after that, there was an outbreak of canine distemper, which is caused by a virus. Late age at infection, however, often causes infectious mononucleosis. Our immune system is constantly monitoring the environment, and the swing between Th1 and Th2 dominance has to be kept in check by regulator T-Cells.

Multiple sclerosis is an immune-mediated disease, meaning the body’s immune system attacks itself. The prevalence rate for those above the 37th parallel is almost double that of those below the 37th parallel: 110 to 140 cases per 100,000 people. In a healthy person this swing is only temporary but in conditions such as MS it has become a chronic shift, where Th1 lymphocytes that have been activated to a particular virus structure also react to other similar structures of human tissue, and in the case of MS this is the myelin sheath. was just chatting with a friend about MS,who says that he heard MS was caused by the herpes virus being sexually transmitted. T-regulatory cells (Tr) are meant to keep this whole process in balance, Tr cells are meant to act as the “brakes” to this whole imbalance, but in MS the brakes that stop the Th1 response are gone due to the chronic viral infection. Vitamin D deficiency is indeed found in those with MS; it is linked to calcium and magnesium deficiency and to osteoporosis. A second form of MS is a chronic and progressive one in which symptoms steadily worsen.

This may explain why people with HIV who are treated with anti-retroviral drugs have a greatly reduced risk of getting MS. Increased antibodies to many different viruses have been found in the sera and cerebrospinal fluid of people with MS. The risk is very small – ­ siblings of an affected person have a only a 2% risk of developing Multiple Sclerosis. This is why it is so important to address all these issues. A role for autoaggressive T cells in MS pathology is further supported by the fact that certain major histocompatibility complex (MHC) class II alleles, in particular the HLA-DR2 haplotype, represent the strongest genetic risk factor, presumably as restriction elements of pathogenic CD4+ T cells and by the therapeutic, though limited, efficacy of immunosuppressive and immunomodulatory agents. Here, we report the spontaneous occurrence of an inflammatory demyelinating disease in a colony of Japanese macaques (JM, Macaca fuscata) at the Oregon National Primate Research Center (ONPRC). If you treat your self as a person and not a disease taking into account all possible causes of MS then I believe you have a greater chance of controlling the long-term outcomes of this disease.

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